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Record detail

One row in GLEAM-DB is one paper (PubMed) × one query variant. This page shows structured labels and provenance for that record, not a final variant classification.

Record identity

Record ID
77c9f7203d18747120f08829
Release version
webdb_threshold_completion_missing10_20260508
PMID
23840885 PubMed
Title
Variations of the UNC13D gene in patients with autoimmune lymphoproliferative syndrome.
Journal
PloS one
Year
2013
DOI
10.1371/journal.pone.0068045
PMC
PMC3698121 PMC

Variant information

This section prioritizes normalized variant expressions where available. Non-standard source strings are not shown as canonical HGVS.

Gene
UNC13D
Query variant
NM_199242.3:c.335G>C
Normalized c.HGVS
c.335G>C
Normalized p.HGVS
p.(Cys112Ser)
Representative genomic HGVS
CM000679.1:g.73838991C>G
Genomic HGVS aliases
CM000679.1:g.73838991C>G; CM000679.2:g.75842910C>G; LRG_122:g.6808G>C; NC_000017.10:g.73838991C>G; NC_000017.11:g.75842910C>G; NC_000017.9:g.71350586C>G; and 1 more

CoGenEx-PM3 evidence

Evidence status is assigned at the PMID × variant level and should not be interpreted as a final variant-level pathogenicity classification.

Evidence status
Other Patient-Level Evidence
Query-evidence confidence
Needs review
Llm Review Not Conclusive For Removal
Phase-confirmed PM3 evidence
No
Phase-unconfirmed biallelic evidence
No
Other patient-level evidence
Yes
PM3 context
Patient-level evidence found, not PM3
PM3 evidence items
0
Allelic configuration type
Other patient-level evidence

No retained PM3 partner variant was recorded for this PMID × variant pair.

Candidate context and target validation

Candidate context windows are places selected for audit because the query or its aliases may be relevant. They are not the same as a validated match to the target c.HGVS or p.HGVS expression.

Candidate context
Candidate context retained: 8 text windows and 2 table windows
Context status
Found in final retained audit context
Text candidate windows
8
Table candidate windows
2
Target c.HGVS validated
Yes
Target p.HGVS validated
Yes
Target validation
Target variant matched with other patient-level evidence

Source provenance

Reviewed source
Main article
Supplement used by audit
No
Supplement available
No
Reviewed document format
NXML/JATS full text
Evidence context scope
Primary audit context
Evidence location
Main article

Source links and copyright boundary

Use the PMID, PMC and DOI links above to inspect the source publication where access is permitted. GLEAM-DB redistributes structured metadata, evidence labels and provenance fields only; it does not redistribute copyrighted full text, supplementary tables, copied source tables, long evidence contexts, raw source documents, raw LLM outputs or internal processing logs.

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