About GLEAM-DB

What is GLEAM-DB?

GLEAM-DB, the Genomic Literature Evidence Atlas Map, is a literature-derived evidence audit resource for ACMG/AMP variant interpretation. It is designed to convert variant-linked literature into reusable, auditable evidence records.

What is CoGenEx-PM3?

CoGenEx-PM3, the Co-occurring Genotype Evidence eXtractor for PM3 allelic-configuration evidence, is the first released evidence module in GLEAM-DB.

Current release

The current release implements CoGenEx-PM3, a PM3-focused module for allelic-configuration evidence. The public unit is one PMID × query_variant evidence record.

Who can use it?

Variant curators, clinical geneticists, rare disease researchers, database developers, benchmark developers and literature-mining researchers.

Citation

Please cite: [Manuscript citation after publication]

Dataset: [Dataset DOI pending]

Contact and maintenance

Contact email, issue reporting and institution details will be added before public release.

GLEAM-DB will be maintained at the current URL for at least five years after publication. Updates will be documented in Release Notes.

The portal provides searchable record-level access, query-specific exports and release-level documentation resources. Full record-level archive files can be deposited as required by publication or repository policy.

Copyright and data use

GLEAM-DB releases structured evidence records and provenance metadata. It does not redistribute copyrighted full-text articles, supplementary tables or raw copyrighted content. Users should consult the original publications for source text and clinical context.